Cutaneous metastases of papillary renal cell carcinoma: A case report and review of the literature

Papillary renal cell carcinoma (RCC) is an uncommon subtype of RCC that is typically encountered at early stages and has a high survival rate. Histopathology typically shows well‐defined papillary architecture with tumor cells lining fibrovascular cores and can be further subdivided into type 1 and...

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Veröffentlicht in:Journal of cutaneous pathology 2019-12, Vol.46 (12), p.960-964
Hauptverfasser: Cardwell, Leah A., Bender, Nicole R., Sokumbi, Olayemi
Format: Artikel
Sprache:eng
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Zusammenfassung:Papillary renal cell carcinoma (RCC) is an uncommon subtype of RCC that is typically encountered at early stages and has a high survival rate. Histopathology typically shows well‐defined papillary architecture with tumor cells lining fibrovascular cores and can be further subdivided into type 1 and type 2 tumors based on cytology and genetic basis. Type 1 tumors have a single layer of basophilic cells and low nuclear atypia, while type 2 tumors have a pseudostratified layer of eosinophilic cells and high nuclear atypia. Some tumors have overlapping features of both types. We present a unique case of cutaneous metastases of papillary RCC with typical papillary architecture in the dermis and review the literature on this rare entity.
ISSN:0303-6987
1600-0560
DOI:10.1111/cup.13546