An Overview on Oroslippery Technique as A Promising Alternative for Tablets used in Dysphagia

Although oral tablets are the most popular dosage forms because of its versatile virtues, the difficulty in their swallowing or dysphagia was the main obstacle in their administration. For this reason, different researches were employed in the formulation of easily swallowed tablets including buccal, sublingual and orodispersible tablet (ODTs). Unfortunately, these oral tables have many drawbacks, like limitation in drug and dose selection, taste masking difficulties in addition to sensitivity to light and moisture and the weak mechanical properties for ODTs. These collectively leads to the development of oroslippery tablets (OSTs) as a suitable alternative for these tablets overcoming their limitations and take the lead for a new generation of tablets that can be easily swallowed intact without the need of water which could be implemented to achieve different release patterns.