Clinical and Immunological Assessment of Renal Transplant Recipients

[...]the identification of molecules by non-invasive, sensitive methods, useful in clinical practice, so-called biomarkers, has been the object of extensive studies by several groups of researchers.10 The nurses' contribution to the success of transplantation is undeniable since it provides specialized care in the protection, promotion, and rehabilitation of the health of candidates, recipients and their families, as well as of living and family donors throughout the life cycle.11 Bearing in mind this framework, the study aimed to assess both clinical and immunological characteristics of renal transplant recipients. [...]PRA discharge is a good indication of the risk of chronic rejection by DSA once again produced in a patient previously with a low PRA dose.14 Anti-HLA or DSA preformed antibody was found to be 66.3% not at risk for rejection. In clinical practice, the main signs and symptoms that characterize the rejection are fever, systemic arterial hypertension, increased volume and pain on the graft, decrease in urinary volume and increase in the value of serum creatinine with no other explanation for the ascent.20 Early diagnosis of acute rejection is crucial for graft function and survival, which requires the care team, especially nursing, to critically evaluate patients in the search for signs and symptoms for intervention in a quick and efficient manner.21 Regarding the HLA immunological characteristics, 46% of the patients had an HLA A compatibility, 47% had two compatibilities in HLA B and 52.3% had one in HLA DR. With regards to the MISMATCH, 26.3% of recipients presented three incompatibilities. [...]the need for a critical and individualized follow-up of the transplanted patient by the professionals to ensure the long-term transplantation success, then guaranteeing that they return their activities with sufficient knowledge to maintain the graft and with self-care skills, enabling an adequate lifestyle and safety for professionals.