Associative clone selection of chinese hamster cells for a complex of quantitative characters

Associative clone selection for a complex of quantitative characters was carried out in populations of cultivated cells. Two hypotetraploid cell populations of Chinese hamster of plus- and minus-direction of selection were studied. The possibility of preserving relatively stable caryotypic structure of polyploid cell populations of spontaneous origin during 20 cell passages. An entropy index was used as a measure of caryotypic heterogeneity and general structure indefinitness of genetic systems – cell populations. A definite correlation between an increase in the genome number in a cell and a change in a set of quantitative characters was determined.