Search for HIV and herpes Inhibitors among the derivatives of polyhedranee and pyridinecarboxylic acid

Search for HIV and herpes Inhibitors among the derivatives of polyhedranee and pyridinecarboxylic acid

It was found that an adamantane derivative (5) inhibits HIV replication as azidothymidin but has immuitostimu/ative properties. The derivatives of isonicotinic acid (2) anil norbornane (4) manifest both antiherpes and immunostimu/ative activity.

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Bibliographische Detailangaben
Veröffentlicht in:Biopolimery i kletka 1999-05, Vol.15 (3), p.207-212
Hauptverfasser: Danilenko, G. I., Rybalko, S. L., Maximov, Ju. M., Sharykina, N. I., Diadiun, S. T., Arkadiev, V. G., Danilenko, V. P., Nesterova, N. V., Guzhova, S. V., Bukhtiarova, T. A., Ovrusky, K. M., Zakhartsev, O. Yu, Gritsak, T. F., Maksimenok, E. V., Vrichanu, N. O.
Format: Artikel
Sprache:eng
Schlagworte:
HIV
Human immunodeficiency virus
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Zusammenfassung:It was found that an adamantane derivative (5) inhibits HIV replication as azidothymidin but has immuitostimu/ative properties. The derivatives of isonicotinic acid (2) anil norbornane (4) manifest both antiherpes and immunostimu/ative activity.
ISSN:0233-7657
1993-6842
DOI:10.7124/bc.00051A