Antiviral activity of trimeric 2',5'-oligoadenylic acid and some of its analogues
The authors have studied the antiviral effect of 2',5'-trioligoadenylate and of its derivatives using several model cell culture systems and viruses: L929 murinc fibroblast cells infected by vaccine virus, established testicular piglet cells inoculated by Aueszki disease virus (ADV) (strai...
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| Veröffentlicht in: | Biopolimery i kletka 1995-09, Vol.11 (5), p.56-60 |
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| container_issue | 5 |
| container_start_page | 56 |
| container_title | Biopolimery i kletka |
| container_volume | 11 |
| creator | Tkachuk, Z. Yu Semernikova, L. I. Tkachuk, V. V. Reshotko, L. M. Mikhailopulo, I. A. Matsuka, G. Kh |
| description | The authors have studied the antiviral effect of 2',5'-trioligoadenylate and of its derivatives using several model cell culture systems and viruses: L929 murinc fibroblast cells infected by vaccine virus, established testicular piglet cells inoculated by Aueszki disease virus (ADV) (strain BUK-628), and the same culture infected with Purdue-115 strain (reference strains of transmissible gastroenteritis virus (TGEV)). So, it is possible to suppose that both 2',5'-trioligoadenylate and its derivative are perspective antiviral preparations acting against DNA- and RNA-containing viruses. |
| doi_str_mv | 10.7124/bc.0003FC |
| format | Article |
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| ispartof | Biopolimery i kletka, 1995-09, Vol.11 (5), p.56-60 |
| issn | 0233-7657 1993-6842 |
| language | eng |
| recordid | cdi_proquest_journals_2306674815 |
| source | EZB-FREE-00999 freely available EZB journals |
| subjects | Antiviral activity Cell culture DNA viruses Gastroenteritis Ribonucleic acid RNA RNA viruses Transmissible gastroenteritis Viruses |
| title | Antiviral activity of trimeric 2',5'-oligoadenylic acid and some of its analogues |
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