Ghrelin as a novel peptide hormone in obesity and weight loss

Ghrelin as a novel peptide hormone in obesity and weight loss

At week 15, 10 chow-fed control rats were kept on the rat chow, 11 DIO rats were kept on the rat chow plus HFD ad libitum and the other 11 DIO rats that were designated as DIO-restricted, were restricted on the intake of the rat chow plus HFD for 5 weeks. Furthermore, the gene expression of gastric...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Proceedings of the Nutrition Society 2013, Vol.72 (OCE1), Article E89
Hauptverfasser: Liu, W., Xiang, M., Harbige, L. S., Ai, H.
Format: Artikel
Sprache:eng
Schlagworte:
Animal behavior
Body weight
Body weight loss
Gene expression
Ghrelin
Menopause
Obesity
Peptides
Rodents
Weight control
Weight loss
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:At week 15, 10 chow-fed control rats were kept on the rat chow, 11 DIO rats were kept on the rat chow plus HFD ad libitum and the other 11 DIO rats that were designated as DIO-restricted, were restricted on the intake of the rat chow plus HFD for 5 weeks. Furthermore, the gene expression of gastric ghrelin in DIO-restricted rats was significantly higher than that of DIO rats and chow-fed control rats (Figure). The body weight and the abdominal fat depots weight were negatively correlated with the levels of plasma ghrelin and gene expression of gastric ghrelin.
ISSN:0029-6651
1475-2719
DOI:10.1017/S0029665113000918