Positive survival trend in metastatic head and neck cutaneous squamous cell carcinoma over four‐decades: Multicenter study

Background This study assessed changes over time of survival of head and neck cutaneous squamous cell carcinoma (HNcSCC) with lymph node metastases. Methods A multicenter analysis of 1301 patients with metastatic HNcSCC treated between 1980 and 2017. Differences in disease‐specific survival (DSS) an...

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Veröffentlicht in:Head & neck 2019-11, Vol.41 (11), p.3826-3832
Hauptverfasser: Hasmat, Shaheen, Ebrahimi, Ardalan, Luk, Peter P., Low, Tsu‐Hui (Hubert), McDowell, Lachlan, Magarey, Matthew J. R., Veness, Michael, Gupta, Ruta, Clark, Jonathan
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Sprache:eng
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Zusammenfassung:Background This study assessed changes over time of survival of head and neck cutaneous squamous cell carcinoma (HNcSCC) with lymph node metastases. Methods A multicenter analysis of 1301 patients with metastatic HNcSCC treated between 1980 and 2017. Differences in disease‐specific survival (DSS) and overall survival (OS) by decade were assessed using multivariate Cox regression. Results Over the study period, we noted an increase in the proportion of patients aged over 80 years (3.9%‐31.7%; P 
ISSN:1043-3074
1097-0347
DOI:10.1002/hed.25912