Influence of morphine sulfate on cocaine-induced coronary vasoconstriction

The effect of morphine sulfate on cocaine-induced coronary vasoconstriction in subjects who underwent cardiac catheterization was studied. Contrary to the hypothesis that a cocaine-morphine combination potentiates the deleterious effects of cocaine on the balance of myocardial oxygen supply and dema...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The American journal of cardiology 2002-10, Vol.90 (7), p.810-811
Hauptverfasser:	Saland, Kenneth E, Hillis, L.David, Lange, Richard A, Cigarroa, Joaquin E
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Intranasal Biological and medical sciences Blood Pressure - drug effects Blood vessels Cocaine Cocaine - administration & dosage Cocaine - adverse effects Coronary Artery Disease - chemically induced Coronary Vessels - drug effects Coronary Vessels - physiology Drug addictions Drug Administration Schedule Female Heart Heart Rate - drug effects Humans Injections, Intravenous Male Medical sciences Middle Aged Morphine - administration & dosage Morphine - adverse effects Narcotics Narcotics - administration & dosage Narcotics - adverse effects Substance-Related Disorders - complications Toxicology Vasoconstriction - drug effects Vasoconstriction - physiology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The effect of morphine sulfate on cocaine-induced coronary vasoconstriction in subjects who underwent cardiac catheterization was studied. Contrary to the hypothesis that a cocaine-morphine combination potentiates the deleterious effects of cocaine on the balance of myocardial oxygen supply and demand, morphine sulfate reverses cocaine-induced coronary arterial vasoconstriction and does not further alter oxygen demand.
ISSN:	0002-9149 1879-1913
DOI:	10.1016/S0002-9149(02)02622-X