Is coronary thrombolysis associated with side effects that significantly compromise clinical benefits?

The in-hospital mortality rate for patients with acute myocardial infarction treated with percutaneous transluminal coronary angioplasty is about 2% compared with 7% to 8% after thrombolytic therapy with streptokinase or tissue-plasminogen activator. This difference may be in part related to certain...

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Veröffentlicht in:	The American journal of cardiology 1996-04, Vol.77 (9), p.756-758
Hauptverfasser:	Gurewich, Victor, Muller, James
Format:	Artikel
Sprache:	eng
Schlagworte:	Angioplasty Angioplasty, Balloon, Coronary - adverse effects Coronary vessels Editorials Fibrinolytic Agents - adverse effects Heart attacks Humans Mortality Myocardial Infarction - drug therapy Myocardial Infarction - therapy Side effects Streptokinase - adverse effects Surgery Survival Rate Thrombolytic Therapy - adverse effects Tissue Plasminogen Activator - adverse effects Treatment Outcome
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Beschreibung
Zusammenfassung:	The in-hospital mortality rate for patients with acute myocardial infarction treated with percutaneous transluminal coronary angioplasty is about 2% compared with 7% to 8% after thrombolytic therapy with streptokinase or tissue-plasminogen activator. This difference may be in part related to certain adverse effects of these thrombolytic agents that have not been given sufficient attention.
ISSN:	0002-9149 1879-1913
DOI:	10.1016/S0002-9149(97)89212-0