Effect of atorvastatin 80 mg on endothelial cell function (forearm blood flow) in patients with pretreatment serum low-density lipoprotein cholesterol levels less than 130 mg/dl

Effect of atorvastatin 80 mg on endothelial cell function (forearm blood flow) in patients with pretreatment serum low-density lipoprotein cholesterol levels less than 130 mg/dl

The effect of 6-week treatment with 80 mg/day atorvastatin on vascular function in the forearm was investigated in 18 patients with mean pretreatment serum low-density lipoprotein cholesterol concentrations of 112 +- 4 mg/dl in a double-blind, placebo-controlled, randomized study. Statin treatment i...

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Veröffentlicht in:The American journal of cardiology 2004-01, Vol.93 (1), p.84
Hauptverfasser: Wassmann, Sven, Ribaudo, Nicole, Faul, Anna, Laufs, Ulrich
Format: Artikel
Sprache:eng
Schlagworte:
Arms
Cells
Cholesterol
Drug therapy
Proteins
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Zusammenfassung:The effect of 6-week treatment with 80 mg/day atorvastatin on vascular function in the forearm was investigated in 18 patients with mean pretreatment serum low-density lipoprotein cholesterol concentrations of 112 +- 4 mg/dl in a double-blind, placebo-controlled, randomized study. Statin treatment improved hyperemic forearm blood flow and decreased serum markers of oxidative stress and inflammation. [PERIODICAL ABSTRACT]
ISSN:0002-9149
1879-1913