Gender differences in blood thrombogenicity in hyperlipidemic patients and response to pravastatin

Thrombotic risk in hyperlipidemic women and its response to lipid therapy is unknown. We prospectively studied 28 men and 29 women with high low-density lipoprotein (LDL) cholesterol during 6 months of therapy with pravastatin. Women had significantly higher high-density lipoprotein (HDL) cholestero...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The American journal of cardiology 1999-09, Vol.84 (6), p.639-643
Hauptverfasser:	Dangas, George, Smith, Donald A, Badimon, Juan J, Unger, Allen H, Shao, John H, Meraj, Perwaiz, Cohen, Adam M, Levine, Daniel, Fallon, John T, Ambrose, John A
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Anticholesteremic Agents - therapeutic use Biological and medical sciences Blood Cholesterol Cholesterol, LDL - blood Drug therapy Female Fibrinogen - metabolism Fibrinolysis - drug effects General and cellular metabolism. Vitamins Humans Hypercholesterolemia - blood Hypercholesterolemia - drug therapy Lipids Male Medical sciences Middle Aged Peptide Fragments - metabolism Pharmacology. Drug treatments Plasminogen Activator Inhibitor 1 - metabolism Platelet Aggregation - drug effects Pravastatin - adverse effects Pravastatin - therapeutic use Prothrombin - metabolism Sex Factors Sexes Thrombin - metabolism Thrombophilia - blood Thrombophilia - drug therapy Triglycerides - blood
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Thrombotic risk in hyperlipidemic women and its response to lipid therapy is unknown. We prospectively studied 28 men and 29 women with high low-density lipoprotein (LDL) cholesterol during 6 months of therapy with pravastatin. Women had significantly higher high-density lipoprotein (HDL) cholesterol (54.2 ± 1.7 vs 39.5 ± 2.2 mg/dl, p
ISSN:	0002-9149 1879-1913
DOI:	10.1016/S0002-9149(99)00408-7