Rhabdomyolysis After Taking Atorvastatin With Gemfibrozil

The findings in this case indicate that atorvastatin, like other DL-3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors, may increase the risk of myositis and rhabdomyolysis when used in combination with gemfibrozil.

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Bibliographische Detailangaben
Veröffentlicht in:	The American journal of cardiology 1998-02, Vol.81 (3), p.368-369
Hauptverfasser:	Duell, P.Barton, Connor, William E, Illingworth, D.Roger
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Atorvastatin Biological and medical sciences Cardiovascular disease Drug Interactions Drug therapy Drug Therapy, Combination Drug toxicity and drugs side effects treatment Female Gemfibrozil - therapeutic use Heptanoic Acids - adverse effects Heptanoic Acids - therapeutic use Humans Hydroxymethylglutaryl CoA Reductases - adverse effects Hydroxymethylglutaryl CoA Reductases - therapeutic use Hypertriglyceridemia - drug therapy Hypolipidemic Agents - therapeutic use Medical sciences Pharmaceuticals Pharmacology. Drug treatments Pyrroles - adverse effects Pyrroles - therapeutic use Rhabdomyolysis - chemically induced Toxicity: nervous system and muscle
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Beschreibung
Zusammenfassung:	The findings in this case indicate that atorvastatin, like other DL-3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors, may increase the risk of myositis and rhabdomyolysis when used in combination with gemfibrozil.
ISSN:	0002-9149 1879-1913
DOI:	10.1016/S0002-9149(97)00907-7