Bitter taste transduced by PLC-beta2-dependent rise in IP3 and alpha-gustducin-dependent fall in cyclic nucleotides

Bitter taste transduced by PLC-beta2-dependent rise in IP3 and alpha-gustducin-dependent fall in cyclic nucleotides

Current evidence points to the existence of multiple processes for bitter taste transduction. Previous work demonstrated involvement of the polyphosphoinositide system and an alpha-gustucin (Galphagust)-mediated stimulation of phosphodiesterase in bitter taste transduction.

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Veröffentlicht in:American Journal of Physiology: Cell Physiology 2001-04, Vol.49 (4), p.C742
Hauptverfasser: Yan, Wentao, Sunavala, Gulshan, Rosenzweig, Sophia, Dasso, Max
Format: Artikel
Sprache:eng
Schlagworte:
Cells
Cellular biology
Metabolism
Taste
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Zusammenfassung:Current evidence points to the existence of multiple processes for bitter taste transduction. Previous work demonstrated involvement of the polyphosphoinositide system and an alpha-gustucin (Galphagust)-mediated stimulation of phosphodiesterase in bitter taste transduction.
ISSN:0363-6143
1522-1563