Nongenomic effect of testosterone on chloride secretion in cultured rat efferent duct epithelia

Short-circuit current (Isc) technique was used to investigate the role of testosterone in the regulation of chloride secretion in cultured rat efferent duct epithelia. Among the steroids tested, only testosterone, and to a lesser extent, 5alpha-dihydrotestosterone (5alpha-DHT), reduced the basal and...

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Veröffentlicht in:	American Journal of Physiology: Cell Physiology 2001-05, Vol.49 (5), p.C1160-C1167
Hauptverfasser:	LEUNG, G. P. H, CHENG-CHEW, S. B, WONG, P. Y. D
Format:	Artikel
Sprache:	eng
Schlagworte:	Androgens Biological and medical sciences Fundamental and applied biological sciences. Psychology Mammalian male genital system Morphology. Physiology Proteins Rodents Steroids Vertebrates: reproduction
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Zusammenfassung:	Short-circuit current (Isc) technique was used to investigate the role of testosterone in the regulation of chloride secretion in cultured rat efferent duct epithelia. Among the steroids tested, only testosterone, and to a lesser extent, 5alpha-dihydrotestosterone (5alpha-DHT), reduced the basal and foreskolin-induced Isc in cultured rat efferent duct epithelia when added to the apical bathing solution.
ISSN:	0363-6143 1522-1563