Novobiocin forms cation-permeable ion channels in rat fetal distal lung epithelium

Novobiocin forms cation-permeable ion channels in rat fetal distal lung epithelium

The effect of novobiocin on ion transport by primary cultures of fetal distal lung epithelium cultured from 20-day gestationally aged rats was studied. Novobiocin was found to affect the bioelectric properties of sodium ion transporting lung epithelium.

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Veröffentlicht in:American Journal of Physiology: Cell Physiology 1993-06, Vol.33 (6), p.C1532-C1537
Hauptverfasser: O'BRODOVICH, H, XIAODONG WANG, CANHUI LI, BIJAN RAFII, CORREA, J, BEAR, C
Format: Artikel
Sprache:eng
Schlagworte:
Anatomy & physiology
Antibacterial agents
Antibiotics. Antiinfectious agents. Antiparasitic agents
Biological and medical sciences
Cellular biology
Ions
Medical sciences
Pharmacology. Drug treatments
Rodents
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Zusammenfassung:The effect of novobiocin on ion transport by primary cultures of fetal distal lung epithelium cultured from 20-day gestationally aged rats was studied. Novobiocin was found to affect the bioelectric properties of sodium ion transporting lung epithelium.
ISSN:0363-6143
1522-1563