CD40 inhibits B cell apoptosis by upregulating bcl-xL expression and blocking oxidant accumulation

The results of a study indicate that CD40 signaling induces a generalized cellular resistance to apoptosis characterized by an upregulation of Bcl-Xl and changes in the intracellular redox potential.

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Bibliographische Detailangaben
Veröffentlicht in:	American Journal of Physiology: Cell Physiology 1997-03, Vol.41 (3), p.C950-C956
Hauptverfasser:	FANG, W, NATH, K. A, MACKEY, M. F, NOELLE, R. J, MUELLER, D. L, BEHRENS, T. W
Format:	Artikel
Sprache:	eng
Schlagworte:	Ageing, cell death Biological and medical sciences Cell physiology Cells Cellular biology Fundamental and applied biological sciences. Psychology Genes Molecular and cellular biology Oxidation
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	The results of a study indicate that CD40 signaling induces a generalized cellular resistance to apoptosis characterized by an upregulation of Bcl-Xl and changes in the intracellular redox potential.
ISSN:	0363-6143 1522-1563