Endogenous nitric oxide is implicated in the regulated of lipolysis through antioxidant-related effect

Endogenous nitric oxide is implicated in the regulated of lipolysis through antioxidant-related effect

We studied the influence of nitric oxide (NO) endogenously produced by adipocytes in lipolysis regulation. Diphenyliodonium (DPI), a nitric oxide synthase (NOS) inhibitor, was found to completely suppress NO synthesis in intact adipocytes and was thus used in lipolysis experiments.

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Veröffentlicht in:American Journal of Physiology: Cell Physiology 2000-11, Vol.48 (5), p.C1603
Hauptverfasser: Gaudiot, Nicolas, Ribiere, Catherine, Jaubert, Anne-Marie, Giudicelli, Yves
Format: Artikel
Sprache:eng
Schlagworte:
Antioxidants
Biochemistry
Free radicals
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Zusammenfassung:We studied the influence of nitric oxide (NO) endogenously produced by adipocytes in lipolysis regulation. Diphenyliodonium (DPI), a nitric oxide synthase (NOS) inhibitor, was found to completely suppress NO synthesis in intact adipocytes and was thus used in lipolysis experiments.
ISSN:0363-6143
1522-1563