Sphingosine 1-phosphate induces Ca2+ transients and cytoskeletal rearrangement in C2C12 myoblastic cells

In many cell systems, sphingosine 1-phosphate (SPP) increases cytosolic Ca2+ concentration ([Ca2+]i) by acting as intracellular mediator and extracellular ligand. Formigli et al investigated the Ca2+ sources of SPP-mediated Ca2+ transients in C2C12 cells and the possible correlation of ion response...

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Veröffentlicht in:	American Journal of Physiology: Cell Physiology 2002-06, Vol.51 (6), p.C1361-C1373
Hauptverfasser:	FORMIGLI, Lucia, FRANCINI, Fabio, ZECCHI ORLANDINI, Sandra, MEACCI, Elisabetta, VASSALLI, Massimo, NOSI, Daniele, QUERCIOLI, Franco, TIRIBILLI, Bruno, BENCINI, Chiara, PIPERIO, Claudia, BRUNI, Paola
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Calcium Cell physiology Cells Cellular biology Fundamental and applied biological sciences. Psychology Ions Molecular and cellular biology Signal transduction
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Zusammenfassung:	In many cell systems, sphingosine 1-phosphate (SPP) increases cytosolic Ca2+ concentration ([Ca2+]i) by acting as intracellular mediator and extracellular ligand. Formigli et al investigated the Ca2+ sources of SPP-mediated Ca2+ transients in C2C12 cells and the possible correlation of ion response to cytoskeletal rearrangement.
ISSN:	0363-6143 1522-1563