Role of protein phosphatases in the regulation of human mast cell and basophil function

Role of protein phosphatases in the regulation of human mast cell and basophil function

Many extracellular stimuli mediate physiological change in target cells by altering the phosphorylation state of proteins. These alterations result from the dynamic interplay of protein kinases, which mediate phosphorylations, and protein phosphatases, which catalyse dephosphorylations.

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Bibliographische Detailangaben
Veröffentlicht in:American Journal of Physiology: Cell Physiology 1999-12, Vol.46 (6), p.C1021-C1028
Hauptverfasser: PEIRCE, M. J, MUNDAY, M. R, PEACHELL, P. T
Format: Artikel
Sprache:eng
Schlagworte:
Biological and medical sciences
Cell physiology
Cellular biology
Enzymes
Fundamental and applied biological sciences. Psychology
Molecular and cellular biology
Proteins
Signal transduction
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Zusammenfassung:Many extracellular stimuli mediate physiological change in target cells by altering the phosphorylation state of proteins. These alterations result from the dynamic interplay of protein kinases, which mediate phosphorylations, and protein phosphatases, which catalyse dephosphorylations.
ISSN:0363-6143
1522-1563