Importance of glucose-6-phosphate dehydrogenase activity in cell death

The intracellular redox potential plays an important role in cell survival. The principal intracellular reductant NADPH is mainly produced by the pentose phosphate pathway by glucose-6-phosphate dehydrogenase (G6PDH), the rate-limiting enzyme, and by 6-phosphogluconate dehydrogenase.

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	American Journal of Physiology: Cell Physiology 1999-05, Vol.45 (5), p.C1121-C1131
Hauptverfasser:	TIAN, W.-N, BRAUNSTEIN, L. D, APSE, K, JIONGDONG PANG, ROSE, M, XIAONI TIAN, STANTON, R. C
Format:	Artikel
Sprache:	eng
Schlagworte:	Ageing, cell death Anatomy & physiology Biological and medical sciences Cell physiology Enzymes Fundamental and applied biological sciences. Psychology Glucose Molecular and cellular biology Proteins
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The intracellular redox potential plays an important role in cell survival. The principal intracellular reductant NADPH is mainly produced by the pentose phosphate pathway by glucose-6-phosphate dehydrogenase (G6PDH), the rate-limiting enzyme, and by 6-phosphogluconate dehydrogenase.
ISSN:	0363-6143 1522-1563