Regulation of Spi 2.1 and 2.2 gene expression after turpentine inflammation : discordant responses to IL-6

Regulation of Spi 2.1 and 2.2 gene expression after turpentine inflammation : discordant responses to IL-6

To examine the role of signal transducer and activation of transcription (STAT) proteins in the divergent regulation of these model genes after induction of APR, we evaluated the proximal promoters of the genes, focusing on STAT binding sites contained in these promoter elements.

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Veröffentlicht in:American Journal of Physiology: Cell Physiology 1999-06, Vol.45 (6), p.C1374-C1382
Hauptverfasser: BERRY, S. A, BERGAD, P. L, STOLZ, A. M, TOWLE, H. C, SCHWARZENBERG, S. J
Format: Artikel
Sprache:eng
Schlagworte:
Biological and medical sciences
Cellular biology
Cytokines
Fundamental and applied biological sciences. Psychology
Genes
Inflammation
Liver
Molecular and cellular biology
Proteins
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Beschreibung
Zusammenfassung:To examine the role of signal transducer and activation of transcription (STAT) proteins in the divergent regulation of these model genes after induction of APR, we evaluated the proximal promoters of the genes, focusing on STAT binding sites contained in these promoter elements.
ISSN:0363-6143
1522-1563