Ceramide triggers intracellular calcium release via the IP3 receptor in Xenopus laevis oocytes

Ceramide triggers intracellular calcium release via the IP3 receptor in Xenopus laevis oocytes

Ceramide, a product of sphingomyelin turnover, is a lipid second messenger that mediates diverse signaling pathways, including those leading to cell cycle arrest and differentiation. The mechanism(s) by which ceramide signals downstream events have not been fully elucidated.

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Veröffentlicht in:American Journal of Physiology: Cell Physiology 1999-10, Vol.46 (4), p.C665-C672
Hauptverfasser: KOBRINSKY, E, SPIELMAN, A. I, ROSENZWEIG, S, MARKS, A. R
Format: Artikel
Sprache:eng
Schlagworte:
Biological and medical sciences
Calcium
Cell physiology
Cells
Fundamental and applied biological sciences. Psychology
Molecular and cellular biology
Proteins
Signal transduction
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Beschreibung
Zusammenfassung:Ceramide, a product of sphingomyelin turnover, is a lipid second messenger that mediates diverse signaling pathways, including those leading to cell cycle arrest and differentiation. The mechanism(s) by which ceramide signals downstream events have not been fully elucidated.
ISSN:0363-6143
1522-1563