EGF inhibits muscarinic receptor-mediated calcium signaling in a human salivary cell line

The effects of epidermal growth factor (EGF) on intracellular calcium responses to the muscarinic agonist carbachol were studied in a human salivary cell line. The results indicate that EGF may play a physiological role in regulating muscarinic receptor-stimulated salivary secretion.

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Veröffentlicht in:American Journal of Physiology: Cell Physiology 2000-10, Vol.48 (4), p.1024-1033
Hauptverfasser: ZHANG, Bin-Xian, YEH, Chih-Ko, HYMER, Tazuko K, LIFSCHITZ, Meyer D, KATZ, Michael S
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Sprache:eng
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Zusammenfassung:The effects of epidermal growth factor (EGF) on intracellular calcium responses to the muscarinic agonist carbachol were studied in a human salivary cell line. The results indicate that EGF may play a physiological role in regulating muscarinic receptor-stimulated salivary secretion.
ISSN:0363-6143
1522-1563