Amino acid control of asparagine synthetase : relation to asparaginase resistance in human leukemia cells

Hutson et al demonstrate that, in both nonleukemic and human leukemia cells, asparagine synthetase mRNA levls, protein content and enzymatic activity are induced after incubation in a culture medium.

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Veröffentlicht in:American Journal of Physiology: Cell Physiology 1997-05, Vol.41 (5), p.C1691-C1699
Hauptverfasser: HUTSON, R. G, KITOH, T, AMADOR, D. A. M, COSIC, S, SCHUSTER, S. M, KILBERG, M. S
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Sprache:eng
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Zusammenfassung:Hutson et al demonstrate that, in both nonleukemic and human leukemia cells, asparagine synthetase mRNA levls, protein content and enzymatic activity are induced after incubation in a culture medium.
ISSN:0363-6143
1522-1563