Reciprocal regulation of cardiac Na-K-ATPase and Na/Ca exchanger : hypertension, thyroid hormone, development
A study tested the hypothesis that cardiac Na/Ca exchanger abundance is regulated in reciprocal fashion to Na-K-ATPase abundance in a number of models known to have altered Na-K-ATPase abundance. The reciprocal regulation of the Na/Ca exchanger and of Na-K-ATPase alpha2-expression provides evidence...
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Veröffentlicht in: | American Journal of Physiology: Cell Physiology 1995-09, Vol.38 (3), p.C675-C682 |
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Hauptverfasser: | , , , |
Format: | Artikel |
Sprache: | eng |
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Online-Zugang: | Volltext |
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Zusammenfassung: | A study tested the hypothesis that cardiac Na/Ca exchanger abundance is regulated in reciprocal fashion to Na-K-ATPase abundance in a number of models known to have altered Na-K-ATPase abundance. The reciprocal regulation of the Na/Ca exchanger and of Na-K-ATPase alpha2-expression provides evidence for a homeostatic mechanism that would oppose the changes in cellular calcium stores driven by the changes in Na-K-ATPase activity. |
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ISSN: | 0363-6143 1522-1563 |