Stimulation of gastric acid secretion by cAMP in a novel α-toxin-permeabilized gland model

Stimulation of gastric acid secretion by cAMP in a novel α-toxin-permeabilized gland model

Yao et al developed a permeabilizied gastric gland model using Staphylococcus alpha-toxin. These studies establish the first permeabilized gland model in which the resting-to-secreting transition can be triggered and show that that adenosine 3',5'-cyclic monophosphate (cAMP)-mediated phosp...

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Veröffentlicht in:American Journal of Physiology: Cell Physiology 1996-07, Vol.40 (1), p.C61-C73
Hauptverfasser: YAO, X, KARAM, S. M, RAMILO, M, RONG, Q, THIBODEAU, A, FORTE, J. G
Format: Artikel
Sprache:eng
Schlagworte:
Biological and medical sciences
Cell physiology
Cellular biology
Digestive system
Fundamental and applied biological sciences. Psychology
Metabolism
Molecular and cellular biology
Proteins
Secretion. Exocytosis
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Zusammenfassung:Yao et al developed a permeabilizied gastric gland model using Staphylococcus alpha-toxin. These studies establish the first permeabilized gland model in which the resting-to-secreting transition can be triggered and show that that adenosine 3',5'-cyclic monophosphate (cAMP)-mediated phosphorylation is correlated with secretory activity.
ISSN:0363-6143
1522-1563