Selective block of gap junction channel expression with connexin-specific antisense oligodeoxynucleotides

Selective block of gap junction channel expression with connexin-specific antisense oligodeoxynucleotides

Selective block of gap junction channel expression with connexin-specific antisense oligodeoxynucleotides was examined in A7r5 cells, a cell line derived from embryonic rat aorta. The data suggest that the 70-pS channel is composed of Cx40, whereas the 108- and 141-pS channels are composed of Cx43.

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Veröffentlicht in:American Journal of Physiology: Cell Physiology 1994-11, Vol.36 (5), p.C1371
Hauptverfasser: Moore, Lisa K, Burt, Janis M
Format: Artikel
Sprache:eng
Schlagworte:
Cellular biology
Coronary vessels
Membranes
Proteins
Rodents
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Zusammenfassung:Selective block of gap junction channel expression with connexin-specific antisense oligodeoxynucleotides was examined in A7r5 cells, a cell line derived from embryonic rat aorta. The data suggest that the 70-pS channel is composed of Cx40, whereas the 108- and 141-pS channels are composed of Cx43.
ISSN:0363-6143
1522-1563