Upregulation of renin-angiotensin system and downregulation of kallikrein in obstructive nephropathy

The effects of prolonged unilateral ureteral obstruction (UUO) on the intrarenal renin-angiotensin and kallikrein-kinin systems in the rat were delineated in a study. Plasma angiotensin II overproduction and kinin deficiency in the pathogenesis of UUO-induced hypertension and intrarenal vasoconstric...

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Veröffentlicht in:American journal of physiology. Renal physiology 1993-05, Vol.33 (5), p.F874
Hauptverfasser: El-Dahr, Samir S, Gee, Jason, Dipp, Susana, Hanss, Basil G
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creator El-Dahr, Samir S
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Hanss, Basil G
description The effects of prolonged unilateral ureteral obstruction (UUO) on the intrarenal renin-angiotensin and kallikrein-kinin systems in the rat were delineated in a study. Plasma angiotensin II overproduction and kinin deficiency in the pathogenesis of UUO-induced hypertension and intrarenal vasoconstriction were implicated by the results.
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ispartof American journal of physiology. Renal physiology, 1993-05, Vol.33 (5), p.F874
issn 1931-857X
1522-1466
language eng
recordid cdi_proquest_journals_230137611
source Alma/SFX Local Collection
subjects Hypertension
Kidneys
Rodents
title Upregulation of renin-angiotensin system and downregulation of kallikrein in obstructive nephropathy
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