Upregulation of renin-angiotensin system and downregulation of kallikrein in obstructive nephropathy
The effects of prolonged unilateral ureteral obstruction (UUO) on the intrarenal renin-angiotensin and kallikrein-kinin systems in the rat were delineated in a study. Plasma angiotensin II overproduction and kinin deficiency in the pathogenesis of UUO-induced hypertension and intrarenal vasoconstric...
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| Veröffentlicht in: | American journal of physiology. Renal physiology 1993-05, Vol.33 (5), p.F874 |
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| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
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| Online-Zugang: | Volltext |
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| Zusammenfassung: | The effects of prolonged unilateral ureteral obstruction (UUO) on the intrarenal renin-angiotensin and kallikrein-kinin systems in the rat were delineated in a study. Plasma angiotensin II overproduction and kinin deficiency in the pathogenesis of UUO-induced hypertension and intrarenal vasoconstriction were implicated by the results. |
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| ISSN: | 1931-857X 1522-1466 |