Augmentation of intrarenal angiotensin II levels by chronic angiotensin II infusion

Augmentation of intrarenal angiotensin II levels by chronic angiotensin II infusion

An investigation of the singular role of elevated angiontensin II (ANG II) in the development of two-kidney, one-clip Goldblatt hypertension in the rat and specifically in the altered intrarenal ANG II levels that occur in the nonclipped kidney is detailed. It was suggested that elevations in circul...

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Veröffentlicht in:American journal of physiology. Renal physiology 1994-01, Vol.35 (1), p.F120
Hauptverfasser: Von Thun, Annette M, Vari, Richard C, El-Dahr, Samir S, Navar, L Gabriel
Format: Artikel
Sprache:eng
Schlagworte:
Hormones
Hypertension
Kidneys
Rodents
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Zusammenfassung:An investigation of the singular role of elevated angiontensin II (ANG II) in the development of two-kidney, one-clip Goldblatt hypertension in the rat and specifically in the altered intrarenal ANG II levels that occur in the nonclipped kidney is detailed. It was suggested that elevations in circulating ANG II serve as the singular mediator of the hypertensive response in ANG II-infused rats.
ISSN:1931-857X
1522-1466