Acid-induced stimulation of Na-Pi cotransport in OK cells : molecular characterization and effect of dexamethasone

Alterations in systemic acid/base balance affect renal Pi excretion. In the present study, the effects of an acidic pH on apical Na-dependent Pi (Na-Pi) cotransport were analyzed using OK cells (opossum kidney cell line). Cells were maintained at either pH 7.4 or 7.1 (altered HC03 concentration at c...

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Veröffentlicht in:American journal of physiology. Renal physiology 1997-09, Vol.42 (3), p.F396-F403
Hauptverfasser: JEHLE, A. W, FORGO, J, BIBER, J, LEDERER, E, KRAPF, R, MURER, H
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Sprache:eng
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Zusammenfassung:Alterations in systemic acid/base balance affect renal Pi excretion. In the present study, the effects of an acidic pH on apical Na-dependent Pi (Na-Pi) cotransport were analyzed using OK cells (opossum kidney cell line). Cells were maintained at either pH 7.4 or 7.1 (altered HC03 concentration at constant PCO2).
ISSN:1931-857X
1522-1466