The electrical resistance breakdown assay determines the role of proteinases in tumor cell invasion

The electrical resistance breakdown of the Madin-Darby canine kidney (MDCK) cell monolayer provides a continuous assay system for cancer invasion that detects functional changes before morphological alterations. Ludwig et al address the question of whether physical contact between tumor cell and epi...

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Veröffentlicht in:American journal of physiology. Renal physiology 2002-08, Vol.52 (2), p.F319-F327
Hauptverfasser: LUDWIG, Thomas, OSSIG, Rainer, GRAESSEL, Susanne, WILHELMI, Marianne, OBERLEITHNER, Hans, SCHNEIDER, Stefan W
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Sprache:eng
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Zusammenfassung:The electrical resistance breakdown of the Madin-Darby canine kidney (MDCK) cell monolayer provides a continuous assay system for cancer invasion that detects functional changes before morphological alterations. Ludwig et al address the question of whether physical contact between tumor cell and epithelial monolayer is a prerequisite for tumor cell invasion.
ISSN:1931-857X
1522-1466