20-hydroxyeicosatetraenoic acid is formed in response to EGF and is a mitogen in rat proximal tubule

20-hydroxyeicosatetraenoic acid is formed in response to EGF and is a mitogen in rat proximal tubule

In a study, the effect of epidermal growth factor (EGF) on proximal tubular 20-hydroxyeicosatetraenoic acid (20-HETE) in relation to EGF in proximal tubule cell preparations was further characterized. It was shown that 20-HETE is a potent mitogen in proximal tubular cells.

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Veröffentlicht in:American journal of physiology. Renal physiology 1995-12, Vol.38 (6), p.F806
Hauptverfasser: Lin, Fangming, Rios, Amelia, Falck, John R, Belosludtsev, Yuri, Schwartzman, Michal Laniado
Format: Artikel
Sprache:eng
Schlagworte:
Biochemistry
Cellular biology
Kidneys
Rodents
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Zusammenfassung:In a study, the effect of epidermal growth factor (EGF) on proximal tubular 20-hydroxyeicosatetraenoic acid (20-HETE) in relation to EGF in proximal tubule cell preparations was further characterized. It was shown that 20-HETE is a potent mitogen in proximal tubular cells.
ISSN:1931-857X
1522-1466