Effect of dietary sodium chloride on insulin receptor number and mRNA levels in rat kidney

Effect of dietary sodium chloride on insulin receptor number and mRNA levels in rat kidney

The effects of different salt intakes on insulin receptor binding and mRNA levels in tissues from rats were studied. An inverse relationship between dietary sodium intake and renal insulin receptor density and mRNA levels suggests the existence of a feedback mechanism that could limit insulin-induce...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:American journal of physiology. Renal physiology 1994-01, Vol.35 (1), p.F31
Hauptverfasser: Sechi, Leonardo A, Griffin, Chandi A, Schambelan, Morris
Format: Artikel
Sprache:eng
Schlagworte:
Insulin
Ribonucleic acid
RNA
Rodents
Salt
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The effects of different salt intakes on insulin receptor binding and mRNA levels in tissues from rats were studied. An inverse relationship between dietary sodium intake and renal insulin receptor density and mRNA levels suggests the existence of a feedback mechanism that could limit insulin-induced sodium retention when extracellular fluid volume is expanded.
ISSN:1931-857X
1522-1466