Stimulation of basolateral Na(positive)-HCO(3negative) cotransporter by angiotensin II in rabbit renal cortex

Stimulation of basolateral Na(positive)-HCO(3negative) cotransporter by angiotensin II in rabbit renal cortex

Experiments were carried out in basolateral membrane vesicles from rabbit renal cortex to analyze directly whether angiotensin II (ANG II) exerts an independent effect on the sodiumpositive-bicarbonatenegative cotransporter. Physiological concentrations of ANG II were identified as a potent, direct...

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Veröffentlicht in:American journal of physiology. Renal physiology 1993-08, Vol.34 (2), p.F195
Hauptverfasser: Eiam-Ong, Somchai, Hilden, Shirley A, Johns, Conrado A, Madias, Nicolaos E
Format: Artikel
Sprache:eng
Schlagworte:
Cellular biology
Kidneys
Rabbits
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Zusammenfassung:Experiments were carried out in basolateral membrane vesicles from rabbit renal cortex to analyze directly whether angiotensin II (ANG II) exerts an independent effect on the sodiumpositive-bicarbonatenegative cotransporter. Physiological concentrations of ANG II were identified as a potent, direct and specific stimulator of the basolateral sodiumpositive-bicarbonatenegative cotransporter.
ISSN:1931-857X
1522-1466