Regulation of adenylyl cyclase in polarized renal epithelial cells by G protein-coupled receptors

Regulation of adenylyl cyclase in polarized renal epithelial cells by G protein-coupled receptors

We employed two guanine nucleotide binding protein (G protein)-coupled receptors known to be targeted to opposite domains in renal epithelial cells to test the hypothesis that the polarized receptor expression of receptors regulates the activity of the receptor's effector molecule, adenylyl cyc...

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Veröffentlicht in:American journal of physiology. Renal physiology 1997-12, Vol.42 (6), p.F883-F891
Hauptverfasser: OKUSA, M. D, HUANG, L, MOMOSE-HOTOKEZAKA, A, HUYNH, L. P, MANGRUM, A. J
Format: Artikel
Sprache:eng
Schlagworte:
Biological and medical sciences
Cellular biology
Fundamental and applied biological sciences. Psychology
Kidneys
Proteins
Vertebrates: urinary system
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Zusammenfassung:We employed two guanine nucleotide binding protein (G protein)-coupled receptors known to be targeted to opposite domains in renal epithelial cells to test the hypothesis that the polarized receptor expression of receptors regulates the activity of the receptor's effector molecule, adenylyl cyclase.
ISSN:1931-857X
1522-1466