Prostaglandin E2 regulation of ion transport is absent in medullary thick ascending limbs from SHR

Prostaglandin E2 regulation of ion transport is absent in medullary thick ascending limbs from SHR

The regulation of HCO3negative and Clnegative absorption by arginine vasopressin (AVP) and prostaglandin E2 (PGE2) was analyzed in perfused, isolated medullary thick ascending limbs from 4-7 week old spontaneously hypertensive rats and Wistar-Kyoto rats. Results of the study indicate that, among oth...

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Veröffentlicht in:American journal of physiology. Renal physiology 1995-07, Vol.38 (1), p.F47
Hauptverfasser: Good, David W, Caflisch, Carlton R, George, Thampi
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Sprache:eng
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Biochemistry
Cellular biology
Genetics
Hypertension
Ions
Proteins
Rodents
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container_title American journal of physiology. Renal physiology
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creator Good, David W
Caflisch, Carlton R
George, Thampi
description The regulation of HCO3negative and Clnegative absorption by arginine vasopressin (AVP) and prostaglandin E2 (PGE2) was analyzed in perfused, isolated medullary thick ascending limbs from 4-7 week old spontaneously hypertensive rats and Wistar-Kyoto rats. Results of the study indicate that, among other things, the effects of PGE2 to stimulate HCO3negative absorption and inhibit Clnegative absorption in the presence of AVP are absent in the medullary thick ascending limbs of spontaneously hypertensive rats.
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ispartof American journal of physiology. Renal physiology, 1995-07, Vol.38 (1), p.F47
issn 1931-857X
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language eng
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source Alma/SFX Local Collection
subjects Biochemistry
Cellular biology
Genetics
Hypertension
Ions
Proteins
Rodents
title Prostaglandin E2 regulation of ion transport is absent in medullary thick ascending limbs from SHR
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