Substrate activation of mechanosensitive, whole cell currents in renal proximal tubule

In a study, isolated, polarized proximal tubule cells of Rana pipiens were voltage clamped and examined for both single-channel and whole cell currents. It was discovered that stretch-activated channels would play a physiological role in proximal tubule potassium homeostasis during sugar and amino a...

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Veröffentlicht in:American journal of physiology. Renal physiology 1993-04, Vol.33 (4), p.F697
Hauptverfasser: Cemerikic, Dusan, Sackin, Henry
Format: Artikel
Sprache:eng
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Zusammenfassung:In a study, isolated, polarized proximal tubule cells of Rana pipiens were voltage clamped and examined for both single-channel and whole cell currents. It was discovered that stretch-activated channels would play a physiological role in proximal tubule potassium homeostasis during sugar and amino acid reabsorption in the proximal tubule of the kidney.
ISSN:1931-857X
1522-1466