The effect of sex and maturation on liver docosahexaenoic acid status in rats

The effect of sex and maturation on liver docosahexaenoic acid status in rats

Women aged less than 40 have higher docosahexaenoic acid (22:6n-3) status(1) and convert more 18:3n-3 to longer chain n-3 polyunsaturated fatty acids (PUFA) than men(2). To test this, we compared the liver fatty acid composition of juvenile and adult male and female rats. Livers were collected, snap...

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Veröffentlicht in:Proceedings of the Nutrition Society 2013, Vol.72 (OCE2), Article E95
Hauptverfasser: Hoile, S. P., Penketh, E., Lillycrop, K. A., Burdge, G. C.
Format: Artikel
Sprache:eng
Schlagworte:
Adults
Age
Biosynthesis
Composition
Docosahexaenoic acid
Fatty acid composition
Fatty acids
Gas chromatography
Lecithin
Liver
Males
Men
Polyunsaturated fatty acids
Puberty
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Zusammenfassung:Women aged less than 40 have higher docosahexaenoic acid (22:6n-3) status(1) and convert more 18:3n-3 to longer chain n-3 polyunsaturated fatty acids (PUFA) than men(2). To test this, we compared the liver fatty acid composition of juvenile and adult male and female rats. Livers were collected, snap frozen and the fatty acid composition of liver phosphatidylcholine (PC) was measured by gas chromatography(6).
ISSN:0029-6651
1475-2719
DOI:10.1017/S0029665113001067