Long-term feeding effect of mono and divalent cation Kappa Carrageenan on some antioxidant, biochemical and histological parameters of growing male rats

Four groups of three-week-old male Sprague-Dawley rats received daily oral dose of pure refined food grade ƙ CGN (500 mg /kg BW/day), ƙ CGN with Na (500 mg/kg BW/day + 10% Na+) , ƙ CGN with Ca (500 mg/kg BW/day + 10% Ca++) or no ƙ CGN as control group for 14 weeks. [...]no significant differences ha...

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Veröffentlicht in:Proceedings of the Nutrition Society 2018-06, Vol.77 (OCE2), Article E44
Hauptverfasser: Farag, A., Zahran, N.M., Salem, A.S., Awney, H.A.
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Zahran, N.M.
Salem, A.S.
Awney, H.A.
description Four groups of three-week-old male Sprague-Dawley rats received daily oral dose of pure refined food grade ƙ CGN (500 mg /kg BW/day), ƙ CGN with Na (500 mg/kg BW/day + 10% Na+) , ƙ CGN with Ca (500 mg/kg BW/day + 10% Ca++) or no ƙ CGN as control group for 14 weeks. [...]no significant differences have been observed in total glycerides, total lipids, high density lipoprotein cholesterol (HDL), low density lipoprotein cholesterol (LDL), liver enzymes, urea, creatinine or hematological parameters between all groups. Serum antioxidant biomarkers in rats treated with ƙ CGN+Ca showed significant decreased (P < 0.05) in both superoxide dismutase (SOD) activity (156.92 ± 9.34 U/ml) compared with control (209.60 ± 32.59 U/ml) and glutathione reductase (GR) activity (3.23 ± 0.16 U/ml) compared with control (7.39 ± 0.38 U/ml).
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subjects Antioxidants
Biomarkers
Calcium
Carrageenan
Cholesterol
Creatinine
Density
Food additives
Glutathione
Glutathione reductase
Glycerides
High density lipoprotein
Lipids
Low density lipoprotein
Parameters
Reductases
Rodents
Sodium
Superoxide dismutase
Urea
title Long-term feeding effect of mono and divalent cation Kappa Carrageenan on some antioxidant, biochemical and histological parameters of growing male rats
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