Hydrogenation reactions catalyzed by colloidal palladium nanoparticles under flow regime

A glycerol colloidal solution of palladium nanoparticles stabilized by PVP (PdPVP, mean diameter of 2.2 ± 0.8 × 10−9 m) was employed under flow conditions for hydrogenation reactions. After optimization, we selected the tube‐in‐tube flow reactor as the more suitable system for this catalytic process due to its ability to regulate the addition of hydrogen. PdPVP nanoparticles were synthesized and fully characterized ((HR)‐TEM, PXRD, EA, and ICP) both in glycerol solution and at solid state. The reduction of different substrates, including nitrobenzene, 4‐phenylbut‐3‐en‐2‐one, and isophorone, was achieved under relatively smooth conditions (5–7 × 105 Pa of H2) in short times (