Renal sensory receptor activation causes prostaglandin-dependent release of substance P

Renal sensory receptor activation causes prostaglandin-dependent release of substance P

The interaction between substance P and prostaglandins was examined by studying the release of substance P and prostaglandin E (PGE) into the renal pelvis before and during renal pelvic perfusion with indomethacin. Data suggest that increased ureteral pressure results in a renal pelvic release of PG...

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Veröffentlicht in:American journal of physiology. Regulatory, integrative and comparative physiology integrative and comparative physiology, 1996-04, Vol.39 (4), p.R720-R727
Hauptverfasser: KOPP, U. C, FARLEY, D. M, SMITH, L. A
Format: Artikel
Sprache:eng
Schlagworte:
Biological and medical sciences
Endocrine system
Fundamental and applied biological sciences. Psychology
Kidneys
Medical research
Vertebrates: urinary system
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Zusammenfassung:The interaction between substance P and prostaglandins was examined by studying the release of substance P and prostaglandin E (PGE) into the renal pelvis before and during renal pelvic perfusion with indomethacin. Data suggest that increased ureteral pressure results in a renal pelvic release of PGE, which facilitates the release of substance P and activation of renal pelvic mechanoreceptor.
ISSN:0363-6119
1522-1490