Effects of a unique conjugate of α-lipoic acid and γ-linolenic acid on insulin action in obese Zucker rats
The purpose of this study was to assess the individual and interactive effects of the antioxidant alphax-lipoic acid (LPA) and the n-6 essential fatty acid gamma-linolenic acid (GLA) on insulin action in insulin-resistant obese Zucker rats. LPA, GLA, and a unique conjugate consisting of equimolar pa...
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| Veröffentlicht in: | American journal of physiology. Regulatory, integrative and comparative physiology integrative and comparative physiology, 2000-02, Vol.47 (2), p.R453-R459 |
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| container_end_page | R459 |
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| container_issue | 2 |
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| container_title | American journal of physiology. Regulatory, integrative and comparative physiology |
| container_volume | 47 |
| creator | PETH, J. A KINNICK, T. R YOUNGBLOOD, E. B TRITSCHLER, H. J HENRIKSEN, E. J |
| description | The purpose of this study was to assess the individual and interactive effects of the antioxidant alphax-lipoic acid (LPA) and the n-6 essential fatty acid gamma-linolenic acid (GLA) on insulin action in insulin-resistant obese Zucker rats. LPA, GLA, and a unique conjugate consisting of equimolar parts of LPA and GLA (LPA-GLA) were administered for 14 days at 10, 30, or 50 mg-kg body wt-1 - day-1. |
| format | Article |
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| fulltext | fulltext |
| identifier | ISSN: 0363-6119 |
| ispartof | American journal of physiology. Regulatory, integrative and comparative physiology, 2000-02, Vol.47 (2), p.R453-R459 |
| issn | 0363-6119 1522-1490 |
| language | eng |
| recordid | cdi_proquest_journals_229782070 |
| source | American Physiological Society Paid; EZB-FREE-00999 freely available EZB journals |
| subjects | Biological and medical sciences Insulin Medical sciences Metabolic diseases Metabolism Muscular system Obesity Rodents |
| title | Effects of a unique conjugate of α-lipoic acid and γ-linolenic acid on insulin action in obese Zucker rats |
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