Effects of hetastarch and mannitol on prolonging survival in stable hypothermia in rats
In rats, prolonged stable hypothermia (tilde24 h at body temperature of 19degC) is characterized by a time-dependent increase in hematocrit, plasma osmolality, and red blood cells fragility and a decrease in plasma volume. These changes impede tissue microcirculation and could limit survival.
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Veröffentlicht in: | American journal of physiology. Regulatory, integrative and comparative physiology integrative and comparative physiology, 2000-04, Vol.47 (4), p.R1040-R1047 |
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container_issue | 4 |
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container_title | American journal of physiology. Regulatory, integrative and comparative physiology |
container_volume | 47 |
creator | LEE, T.-F WESTLY, J WANG, L. C. H |
description | In rats, prolonged stable hypothermia (tilde24 h at body temperature of 19degC) is characterized by a time-dependent increase in hematocrit, plasma osmolality, and red blood cells fragility and a decrease in plasma volume. These changes impede tissue microcirculation and could limit survival. |
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Regulatory, integrative and comparative physiology</title><description>In rats, prolonged stable hypothermia (tilde24 h at body temperature of 19degC) is characterized by a time-dependent increase in hematocrit, plasma osmolality, and red blood cells fragility and a decrease in plasma volume. These changes impede tissue microcirculation and could limit survival.</description><subject>Biological and medical sciences</subject><subject>Circulatory system</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Hypothermia</subject><subject>Plasma</subject><subject>Rodents</subject><subject>Thermoregulation. Hibernation. Estivation. 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Ecophysiology and environmental effects</topic><topic>Vertebrates: anatomy and physiology, studies on body, several organs or systems</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>LEE, T.-F</creatorcontrib><creatorcontrib>WESTLY, J</creatorcontrib><creatorcontrib>WANG, L. C. H</creatorcontrib><collection>Pascal-Francis</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Chemoreception Abstracts</collection><collection>Physical Education Index</collection><collection>Toxicology Abstracts</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><jtitle>American journal of physiology. 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ispartof | American journal of physiology. Regulatory, integrative and comparative physiology, 2000-04, Vol.47 (4), p.R1040-R1047 |
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source | American Physiological Society; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
subjects | Biological and medical sciences Circulatory system Fundamental and applied biological sciences. Psychology Hypothermia Plasma Rodents Thermoregulation. Hibernation. Estivation. Ecophysiology and environmental effects Vertebrates: anatomy and physiology, studies on body, several organs or systems |
title | Effects of hetastarch and mannitol on prolonging survival in stable hypothermia in rats |
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