Effects of hetastarch and mannitol on prolonging survival in stable hypothermia in rats
In rats, prolonged stable hypothermia (tilde24 h at body temperature of 19degC) is characterized by a time-dependent increase in hematocrit, plasma osmolality, and red blood cells fragility and a decrease in plasma volume. These changes impede tissue microcirculation and could limit survival.
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Veröffentlicht in: | American journal of physiology. Regulatory, integrative and comparative physiology integrative and comparative physiology, 2000-04, Vol.47 (4), p.R1040-R1047 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | In rats, prolonged stable hypothermia (tilde24 h at body temperature of 19degC) is characterized by a time-dependent increase in hematocrit, plasma osmolality, and red blood cells fragility and a decrease in plasma volume. These changes impede tissue microcirculation and could limit survival. |
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ISSN: | 0363-6119 1522-1490 |