Control of pulmonary surfactant secretion from type II pneumocytes isolated from the lizard Pogona vitticeps

Pulmonary surfactant, a mixture consisting of lipids and proteins and secreted by type 11 cells, functions to reduce the surface tension of the fluid lining of the lung, and thereby decreases the work of breathing. In mammals, surfactant secretion appears to be influenced primarily by the sympatheti...

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Veröffentlicht in:American journal of physiology. Regulatory, integrative and comparative physiology integrative and comparative physiology, 1999-12, Vol.46 (6), p.R1705-R1711
Hauptverfasser: WOOD, P. G, LOPATKO, O. V, ORGEIG, S, CODD, J. R, DANIELS, C. B
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Sprache:eng
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Zusammenfassung:Pulmonary surfactant, a mixture consisting of lipids and proteins and secreted by type 11 cells, functions to reduce the surface tension of the fluid lining of the lung, and thereby decreases the work of breathing. In mammals, surfactant secretion appears to be influenced primarily by the sympathetic nervous system and changes in ventilatory pattern.
ISSN:0363-6119
1522-1490