Time-dependent physiological regulation of rodent and ovine placental glucose transporter (GLUT-1) protein

To examine the in vivo and in vitro time-dependent effects of glucose on placental glucose transporter (GLUT-1) protein levels, we employed Western blot analysis using placenta from the short-term streptozotocin-induced diabetic pregnancy (STZ-D), uterine artery ligation-intrauterine growth restrict...

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Veröffentlicht in:	American journal of physiology. Regulatory, integrative and comparative physiology integrative and comparative physiology, 1998-02, Vol.43 (2), p.R339-R347
Hauptverfasser:	DAS, U. G, FAROUK SADIQ, H, SOARES, M. J, HAY, W. W, DEVASKAR, S. U
Format:	Artikel
Sprache:	eng
Schlagworte:	Anatomy & physiology Biological and medical sciences Diabetes Embryology: invertebrates and vertebrates. Teratology Fetal membranes Fetuses Fundamental and applied biological sciences. Psychology General aspects. Development. Fetal membranes Glucose Hypoglycemia Proteins Rodents Sheep
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Beschreibung
Zusammenfassung:	To examine the in vivo and in vitro time-dependent effects of glucose on placental glucose transporter (GLUT-1) protein levels, we employed Western blot analysis using placenta from the short-term streptozotocin-induced diabetic pregnancy (STZ-D), uterine artery ligation-intrauterine growth restriction (IUGR) rat models, pregnant sheep exposed to chronic maternal glucose and insulin infusions, and the HRP.1 rat trophoblastic cell line exposed to differing concentrations of glucose.
ISSN:	0363-6119 1522-1490