No evidence for HPA reset in adult sheep with high blood pressure due to short prenatal exposure to dexamethasone

No evidence for HPA reset in adult sheep with high blood pressure due to short prenatal exposure to dexamethasone

Exposure of pregnant ewes to dexamethasone, for only two days at 27 days of gestation, results in adult offspring with high blood pressure. Hemorrhage stress was used to determine whether in these animals the responsiveness of the hypothalamo-pituitary-adrenal axis is altered.

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:American journal of physiology. Regulatory, integrative and comparative physiology integrative and comparative physiology, 2002-02, Vol.51 (2), p.R343-R350
Hauptverfasser: DODIC, Miodrag, PEERS, Arianne, MORITZ, Karen, HANTZIS, Vicky, WINTOUR, E. Marelyn
Format: Artikel
Sprache:eng
Schlagworte:
Arterial hypertension. Arterial hypotension
Biological and medical sciences
Blood and lymphatic vessels
Cardiology. Vascular system
Experimental diseases
Hypertension
Medical research
Medical sciences
Pituitary gland
Sheep
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Exposure of pregnant ewes to dexamethasone, for only two days at 27 days of gestation, results in adult offspring with high blood pressure. Hemorrhage stress was used to determine whether in these animals the responsiveness of the hypothalamo-pituitary-adrenal axis is altered.
ISSN:0363-6119
1522-1490