Endothelin-A receptors and NO mediate decrease in arterial pressure during recovery from restraint

We investigated the role of central endothelin-A(ETA) receptors and nitric oxide (NO) in regulating arterial pressure during restraint stress and recovery from stress. Rats received intracerebroventricular (icv) injections of the ETA receptor antagonist BQ123 (24 mug/kg) and were then subjected to t...

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Veröffentlicht in:	American journal of physiology. Regulatory, integrative and comparative physiology integrative and comparative physiology, 2002-03, Vol.51 (3), p.R881-R889
Hauptverfasser:	YIP, Avery W. C, KRUKOFF, Teresa L
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Blood pressure Chemical elements Fundamental and applied biological sciences. Psychology Heart Motor control and motor pathways. Reflexes. Control centers of vegetative functions. Vestibular system and equilibration Nervous system Stress Vertebrates: nervous system and sense organs
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Zusammenfassung:	We investigated the role of central endothelin-A(ETA) receptors and nitric oxide (NO) in regulating arterial pressure during restraint stress and recovery from stress. Rats received intracerebroventricular (icv) injections of the ETA receptor antagonist BQ123 (24 mug/kg) and were then subjected to two restraint-rest cycles (1 h of restraint and 1 h of rest/cycle).
ISSN:	0363-6119 1522-1490